DNA Makes RNA Makes Innate Immunity
نویسنده
چکیده
Microbial DNA in the cytosol induces production of interferon-beta (IFN-beta) and an innate immune response. Chiu et al. (2009) now implicate cytosolic DNA-dependent RNA polymerase III as the DNA sensor linking DNA release by pathogenic bacteria and viruses in the host cell cytosol to IFN-beta production and innate immunity.
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ورودعنوان ژورنال:
- Cell
دوره 138 شماره
صفحات -
تاریخ انتشار 2009